DIM for Men’s Health
The wisdom that prevention is better than cure is applicable to food supplements. Diindolylmethane, the nutraceutical, is one of such examples. It may become a salvage for people with hormonal imbalance. In this article we will speak about its necessity and role in men’s health.
The advantages of using diindolylmethane for men consist in rising up testosterone rates. This is a good prophylaxis of cardiovascular diseases and hormone sensitive cancers. While the majority of clinical trials are concentrated on cancer averting and curing, scientific researches of the Cancer Institute in the USA show its other benefits too.
Being firstly a female purposed preparation, it becomes more popular supplement for enhancement of overall men’s health.
Estrogen Importance for Men’s Health
Estrogen is a hormone which plays an important role in men’s health. Low levels prepossess men to such disease as osteopenia and lead to bone destruction. More than average norm provokes stroke and coronary artery insufficiency. High levels threatens prostate gland enlargement and cancer, especially in case of low free testosterone blood levels.
In people with chronic heart failure low estradiol, a type of estrogen, leads to mortality during the following years in 317% of cases. High level of estradiol is a reason of death 133% of men. Thusly, optimal estrogen levels are vital for life.
Estrogen is produced in the brain, liver, muscles through the ferment aromatase, which converts testosterone into estradiol. Diabetic usually suffer from high rates of estrogen.
Increased aromatase activity leads to conversion of testosterone into estrogen causing draining of testosterone. It becomes a reason of weakness, low sexual activity and multiple erectile problems, mood swinging, obesity and other health problems. Men with a lack of aromatase become estrogen drained.
There are natural and medical ways to balance the hormones. Certain food, supplements, and healthy life mode are vital for good work of males organism and longevity.
What Is DIM (Diindolylmethane)?
Diindolylmethane (DIM) is a molecule generated in the body during digestion process of meals that contain the nutrient indole-3-carbinol. It makes positive impact on the human immune system.
DIM is able to induce aryl hydrocarbon receptor (AhR), which responds for toxic attack affecting the organism. AhR activation activity happens when the immune system is imperfect and DIM helps to stimulate this process. AhR also assistants production of Natural killer (NK) which protects lesion and instability of human’s immunity.
It mainly focuses on protection from malignancy (breasts, uterine, colorectal), benign prostatic hyperplasia and premenstrual syndrome treating.
Is It Safe?
DIM is absolutely safe for men in small doses which come in food. This is approximately 2-24 mg of diindolylmethane.
People who use it in quality of supplement should be aware of the correct dosages and consult with healthcare provider before starting the course. Large doses of diindolylmethane are not safe. 600 mg daily promote low sodium levels in particular cases. Adverse effects of the doses less than 300 mg per day were not found.
It can be used by pregnant and breastfeeding women and children in very small amounts. The safeness of usage in hormone-sensitive states like cancer, endometriosis, fibroids need more scientific researches, therefore the preparation hasn’t been recommended yet for these cases.
What Does DIM Do for Men?
The clear mechanism of action is still under scientific control. Doctor’s literary works say that DIM for men assistants balancing the sex hormones estrogen and testosterone.
When estrogen is being decomposed in the organism, its metabolites may be salubrious or destructive. DIM corrects estrogen breakdown to positive side. Curative estrogen metabolites are characterized by antioxidative features that prevent free-radical damaging in the heart and brain. DIM rejects negative impact of estrogen metabolites, protecting from fattiness, malignant swellings and forfeiting of sexual energy in men.
So, what does DIM do for men? This supplement:
- successfully regulates testosterone levels in males organism;
- supports libido;
- serves for general well-being and active sexual life;
- makes rejuvenating body effect;
- struggles against adiposity;
- enlarges muscles in combination with gym exercises.
Scientific researches about superiority of DIM go on. Today online reviews show that DIM is a popular food supplement among males and females.
How to Take Diindolylmethane?
Generally, DIM should be taken in dose 100-200 mg daily for help with the aging process. People with normal weight should take 100 mg per day. Overweight, people with inflammatory processes or those who are under transgenerational transfer risk of cancer diseases should take 200 mg after preliminary medical consultation. Males who have been actively trying to lose weight and build muscles mass should enlarge the dose up to 400 mg.
Correct dosages should be settled individually by a personal healthcare provider. They may vary depending on individual factors and habits too. Doctor should inform about the reaction of particular food products with estrogen and correct the patient’s life style.
|Mode of life||Estrogen level|
Fattiness increases estrogen rates and confines the efficiency of aromatase inhibitors. Over-consuming of spare calories increases metabolic activity in the organism and excessive free radical formation. Free radicals damage cells and cause genetic mutations which lead to cancer.
Alcohol and drugs
Alcohol increases estrogen levels, especially with estrogen replacement therapy. Alcohol and drugs destroy liver which leads to enlarging of estrogen due to lack of its breakdown.
Any source of caffeine
It rises up estrogen level in any age. A cup in a day is enough, 500 mg of caffeine (4-5 cups of coffee) and more enlarge estrogen level in 70%.
Sport helps to balance hormones and regulates a health weight.
Natural Sources of Diindolylmethane (DIM)
DIM is available in supplement form, though it is not always recommended by doctors. Food that contain I3C also include such chemopreventive compound as sulforaphane which makes more positive effect.
Natural sources is an easy and available way of receiving DIM, but its amounts are too low and barely make a serious impact on general health. For achieving evident results the food should be eaten in big amounts. Thermal effect takes away part of plant’s useful features. Thus, organism receives not that many benefits, especially when it needs hormonal balance urgently.
Cruciferous vegetables are rich in fiber, carotenoids, folic acid, calcium, vitamin C. They also include phytonutrients (like DIM) that rise up the immunity resistance of the organism. Diindolylmethane is being produced during digestion process of indole-3-carbinol, the compound found in the following vegetables:
- pak choi;
- brussel sprouts;
- turnip-rooted cabbage;
- curled mustard;
- French turnip;
- Japanese radish (wasabi);
Herbal supplement comes the best way of taking DIM. Large amounts of natural food and thermal action (boiling, frying, microwaving etc) may reduce DIM accessibility from natural sources. 1-2 capsules are very easy for taking and guarantee the claimed effect.
Most scientific studies and researches have used for trials the certificated product BioResponse which is manufactured by the company BioResponse Nutrients. It has been patented in the USA and can be bought online on the site of the producer. For foreign purchasers it is not a problem to find supplements that contain BioResponse DIM.
Its generic version is available too, though it appears to be not very successful remedy due to discovered absorption problems. If generic does not show any results after few months of usage, there is a sense to change it to the original preparation.
Veggie supplements have many variations: Jarrow Formulas, Source Naturals, Ultra DIM etc. There are females formulas: Rainbow Light Multivitamin, Women’s Life Force Multiple and other.
The level of estrogen in mature males rises up comparing to a younger age. It becomes a reason of erectile and fecundity problems, cardiovascular diseases.
The benefits of DIM lay in restoring acceptable elaboration of estrogen. Taking supplements regularly reduces comedones, enhances temper and rises up sexual energy.
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What Is the Best DIM Form?
Some foods contain natural DIM. To receive the necessary doses for chemical process a person should eat about 2 pounds of plant every day. Therefore, supplements come as the most convenient way of consuming the plant-based chemical.
DIM additives are mostly standard ones and do not contain extra compounds. Particular DIM supplements include bioperine (piperine composition taken out of black pepper essence) for better absorption. But the feasibility of black pepper is not well tested yet.
Brand DIM producers also add vitamin E in order to increase biological availability.
Vegetarian capsules may also contain plant fiber, rice flour, silicon dioxide, ascorbyl palmitate. Consult with healthcare provider regarding every particular supplement before using DIM.
Does It Have Side Effects?
Taking high doses (300 mg and above) threatens to various side effects. Possible ones include:
- headaches (especially in the beginning of course);
- hematuria (dark urine);
- stomach upsets;
- dermatological conditions.
DIM interacts with prescription drugs, therefore it is better to exclude the supplement during any curing course. It includes CYP3A4 and possibly affects the serum concentration of drugs metabolized by the ferment. DIM is determined as MDR1 inducer which affects drugs transportation mediated by this protein. Hormonal disturbance may also appear.